DPY30 Antibody (YA6990)
(Synonyms: Dpy-30-like protein antibody; Dpy-30L antibody; DPY30 antibody; DPY30_HUMAN antibody; HDPY-30 antibody; Protein dpy-30 homolog antibody; Saf19 antibody)DPY30 Antibody (YA6990) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DPY30.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500 | 1:100 |
Product Details
DPY30 Antibody (YA6990) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DPY30.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 11kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 11kDa
SwissProt: Q9C005 Human
Recombinant protein within mouse DPY30 aa 1-99 / 99.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DPY30 is an As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and histone H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. May also play an indirect or direct role in endosomal transport
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Subcellular Localization
Nucleus,Golgi apparatus, trans-Golgi network
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Isoforms & Post-Translational Modification
Q99LT0: 99 amino acids, molecular weight 11213 Da.
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Subunit
Homodimer
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SwissProt ID
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Synonyms
Dpy-30-like protein antibody; Dpy-30L antibody; DPY30 antibody; DPY30_HUMAN antibody; HDPY-30 antibody; Protein dpy-30 homolog antibody; Saf19 antibody
Documentation