DUPD1 (DUSP27) Antibody (YA8378)

Cat. No.: HY-P88694: Data Sheet User Guide for Antibodies
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DUPD1 (DUSP27) Antibody (YA8378) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to DUPD1 (DUSP27).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

DUPD1 (DUSP27) Antibody (YA8378) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to DUPD1 (DUSP27).

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 25.2 kDa

Species Reactivity

Human, Mouse

SwissProt ID

Q68J44

Immunogen

Full length human recombinant protein of human DUPD1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (PubMed:17498703). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (By similarity). Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity)

Subcellular Localization：Cytoplasm,Nucleus

Isoforms & Post-Translational Modification：Q68J44: 220 amino acids, molecular weight 25336 Da.

Subunit：Homodimer (PubMed:21543850)

Synonyms

DUSP27; FMDSP

Documentation

User Guide for Antibodies (1077 KB)