Elongation factor 2 Antibody (YA963)
(Synonyms: EEF2; EF2; Elongation factor 2; EF-2)Elongation factor 2 Antibody (YA963) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Elongation factor 2.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Monkey, Rat
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:200 |
Product Details
Elongation factor 2 Antibody (YA963) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Elongation factor 2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Monkey, Rat
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Observed Molecular WeightObserved band size: 95 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 95 kDa
Entrez Gene: 1938 Human ; 13629 Mouse ; 29565 Rat
SwissProt: P13639 Human ; P58252 Mouse ; P05197 Rat
OMIM: 609306 Human
Purified recombinant human eEF2 protein fragments expressed in E.coli.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Elongation factor 2 catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome[1].
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Subcellular Localization
Cytoplasm; Nucleus
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Subunit
Binds to 80S ribosomes (PubMed:27115996, PubMed:30355441). Actively translating ribosomes show mutually exclusive binding of eIF5a (EIF5A or EIF5A2) and EEF2/eEF2 (PubMed:27115996).
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SwissProt ID
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Synonyms
EEF2; EF2; Elongation factor 2; EF-2
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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