Endothelin A Receptor Antibody
(Synonyms: ETA, ETRA, EDNRA, Endothelin-1 receptor, Endothelin receptor type A, ET-A, ETA-R, hET-AR)
Based on 1 Customer Validation
Endothelin A Receptor Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Endothelin A Receptor.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF
-
Reactivity :
Human, Mouse
-
Formulation:
Supplied in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:100-500 |
Product Details
Endothelin A Receptor Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Endothelin A Receptor.
-
Host Rabbit
-
Clonality Polyclonal
-
Species ReactivityHuman, Mouse
-
Observed Molecular WeightObserved band size: 69; 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 48 kDa
Synthetic peptide corresponding to the C-term region of human Endothelin A Receptor.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Endothelin A Receptor is a Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3
-
Subcellular Localization
Cell membrane
-
Expression
Tissue_Specificity: Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels. -
Isoforms & Post-Translational Modification
Endothelin A Receptor has 5 isoforms, P25101-1: amino acid length is 427, molecular weight is 48722 Da (predicted); P25101-2: amino acid length is 161, molecular weight is 17820 Da (predicted); P25101-3: amino acid length is 187, molecular weight is 20763 Da (predicted); P25101-4: amino acid length is 318, molecular weight is 36489 Da (predicted); P25101-5: amino acid length is 202, molecular weight is 23803 Da (predicted).
-
Subunit
Interacts with HDAC7 and KAT5
-
SwissProt ID
-
Synonyms
ETA, ETRA, EDNRA, Endothelin-1 receptor, Endothelin receptor type A, ET-A, ETA-R, hET-AR
Documentation
Powered by Bioz
