EpCAM Antibody (YA3470)
(Synonyms: 17 1A antibody; 323/A3 antibody; Adenocarcinoma associated antigen antibody; Antigen identified by monoclonal antibody; AUA1 antibody; CD326 antibody; Cell surface glycoprotein Trop 1 antibody; CO17A antibody; DIAR5 antibody; EGP 2 antibody; EGP antibody; EGP2 antibody; EGP314 antibody; EGP40 antibody; EPCAM antibody; Epithelial cell adhesion molecule antibody; ESA antibody; GA733 1 antibody; gp4 antibody; hEGP 2 antibody; hEGP314 antibody; HNPCC8 antibody; KS1/4 antibody; KSA antibody; Ly74 antibody; M1S 1 antibody; M1S2 antibody; M4S1 antibody; mEGP314 antibody; MIC18 antibody; MK 1 antibody; Protein 289A antibody; TACD1 antibody; TACSTD1 antibody; TROP1 antibody)
Based on 1 Customer Validation
EpCAM Antibody (YA3470) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EpCAM.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:200 | 1:500 | 1:500-1000 |
Product Details
EpCAM Antibody (YA3470) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EpCAM.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 35 kDa
Recombinant protein within human EpCAM aa1-295.
affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EpCAM (CD326) is a transmembrane glycoprotein expressed on the surface of epithelial cells and serves as a classic marker for epithelial cells and epithelial-derived tumors. It plays a role in cell adhesion, the regulation of proliferation, and the maintenance of tumor stemness, holding significant value in tumor diagnosis, circulating tumor cell detection, cancer stem cell research, and the development of targeted therapies.
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Subcellular Localization
Lateral cell membrane; Single-pass type I membrane protein; Cell junction, tight junction
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Expression
Tissue_specificity:This gene is highly and selectively expressed in undifferentiated embryonic stem cells (ESCs) , but not in differentiated ESCs. Once ESCs differentiate, its protein level rapidly declines. This gene is expressed on almost all epithelial cell membranes, but not on mesoderm or neural cell membranes. It has also been found on the surface of adenocarcinomas.
Positive sample: Human colon tissue, HT-29. -
Subunit
Monomer. Interacts with phosphorylated CLDN7
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SwissProt ID
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Synonyms
17 1A antibody; 323/A3 antibody; Adenocarcinoma associated antigen antibody; Antigen identified by monoclonal antibody; AUA1 antibody; CD326 antibody; Cell surface glycoprotein Trop 1 antibody; CO17A antibody; DIAR5 antibody; EGP 2 antibody; EGP antibody; EGP2 antibody; EGP314 antibody; EGP40 antibody; EPCAM antibody; Epithelial cell adhesion molecule antibody; ESA antibody; GA733 1 antibody; gp4 antibody; hEGP 2 antibody; hEGP314 antibody; HNPCC8 antibody; KS1/4 antibody; KSA antibody; Ly74 antibody; M1S 1 antibody; M1S2 antibody; M4S1 antibody; mEGP314 antibody; MIC18 antibody; MK 1 antibody; Protein 289A antibody; TACD1 antibody; TACSTD1 antibody; TROP1 antibody
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Research Field
Tags & Cell Markers
Documentation
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