ER81 Antibody (YA4843)
(Synonyms: ETV1; ER81; ETS translocation variant 1; Ets-related protein 81)ER81 Antibody (YA4843) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to ER81.
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Host:
Mouse
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Application:
WB, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
ER81 Antibody (YA4843) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to ER81.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 55 kDa;
Purified recombinant fragment of ER81 (aa1-191) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ER81 transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH)[1].
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes -
Isoforms & Post-Translational Modification
P50549 has 6 isomers: P50549-1: 55131 Da (predicted); P50549-2: 53083 Da (predicted); P50549-3: 52474 Da (predicted); P50549-4: 43455 Da (predicted); P50549-5: 48168 Da (predicted); P50549-6: 50217 Da (predicted).
Sumoylated;Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5; phosphorylation activates transcriptional activity -
SwissProt ID
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Synonyms
ETV1; ER81; ETS translocation variant 1; Ets-related protein 81
Documentation
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