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ETAA1 Antibody (YA2781)(PBS only)

(Synonyms: ETAA16)

ETAA1 Antibody (YA2781) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ETAA1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • ETAA1 Antibody (YA2781)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

ETAA1 Antibody (YA2781) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ETAA1.

  • Host Rabbit
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 103 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 103 kDa
Immunogen

Recombinant protein of human ETAA1

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    ETAA1 is a Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets[1][2][3][4].

  • Subcellular Localization

    Nucleus

  • Expression


    Tissue_specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines

  • Subunit

    Interacts (via RBM1 motif) with RPA1 (PubMed:27601467, PubMed:27723717, PubMed:27723720). Interacts (via RBM2 motif) with RPA2 (PubMed:27601467, PubMed:27723717, PubMed:27723720).

  • SwissProt ID

    Q9NY74

  • Gene ID
    54465 [NCBI]
  • Synonyms

    ETAA16

  • Research Field

    Cancer

ETAA1 Antibody (YA2781)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • ETAA1 Antibody (YA2781)(PBS only) Product Image
    1/16
  • ETAA1 Antibody (YA2781)(PBS only) Product Image