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FDPS Antibody (YA2817)(PBS only)

(Synonyms: FPS; FPPS; POROK9)

FDPS Antibody (YA2817) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FDPS.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Hamster

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • FDPS Antibody (YA2817)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500-1:1000 1:50-1:100

Product Details

Description

FDPS Antibody (YA2817) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FDPS.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Hamster Predicted Reactivity: Human
    Info
    Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
  • Observed Molecular Weight
    Observed band size: 48 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 48 kDa
Species Reactivity Database

Entrez Gene: 2224 Human

SwissProt: P14324 Human ;

Immunogen

A synthetic peptide of human FDPS

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate

  • Subcellular Localization

    Cytoplasm

  • Isoforms & Post-Translational Modification

    P14324 has 2 isomers: P14324-1: 48275 Da (predicted); P14324-2: 40532 Da (predicted).

  • Subunit

    Homodimer. Interacts with RSAD2

  • SwissProt ID

    P14324

  • Gene ID
    2224 [NCBI]
  • Synonyms

    FPS; FPPS; POROK9

  • Research Field

    Cardiovascular

FDPS Antibody (YA2817)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • FDPS Antibody (YA2817)(PBS only) Product Image