FGF19 Antibody
(Synonyms: UNQ334/PRO533, FGF19, Fibroblast growth factor 19, FGF-19)FGF19 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to FGF19.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
FGF19 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to FGF19.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 24 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 24 kDa
Synthetic peptide corresponding to the center region of human FGF19.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FGF19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Induction: Induced by the bile acids receptor NR1H4 that binds and activates a NR1H4-responsive element within intron 2. -
Isoforms & Post-Translational Modification
FGF19 has an amino acid length of 216, molecular weight is 24003 Da.FGF19 的氨基酸个数为 216 个，分子量为 24003 Da。
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Subunit
Interacts with FGFR1, FGFR2, FGFR3 and FGFR4.
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SwissProt ID
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Synonyms
UNQ334/PRO533, FGF19, Fibroblast growth factor 19, FGF-19
Documentation
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