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FMNL1 Antibody (YA8924)

(Synonyms: C17orf1, C17orf1B, FMNL, FRL1, FMNL1, Formin-like protein 1, CLL-associated antigen KW-13, Leukocyte formin)
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FMNL1 Antibody (YA8924) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FMNL1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, IF-Tissue, IP, ELISA

  • Reactivity :

    human

  • Formulation:

    Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.

  • Conjugation:
    Non-conjugated
  • FMNL1 Antibody (YA8924) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
IF-Tissue Info
IF-Tissue: Immunofluorescence-Tissue
IP Info
IP: Immunoprecipitation
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:100-1000 1:50-500 1:50-500 1-2μg per 100-500μg Total protein 1:30-3000

Product Details

Description

FMNL1 Antibody (YA8924) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FMNL1.

  • Host Mouse
  • Species Reactivity
    human
  • Calculated Molecular Weight Predicted band size: 122 kDa
Species Reactivity Database

OMIM: 604656

Immunogen

A synthesized peptide derived from human FMNL1.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at 2-8°C for 1 year, do not freeze.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    FMNL1 plays a role in actin cytoskeleton dynamics and regulation of cell shape[1].

  • Subcellular Localization

    Cytoplasm; Cell membrane; Cytoplasmic vesicle, phagosome

  • Expression


    Tissue_Specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

  • Isoforms & Post-Translational Modification

    FMNL1 has 3 isoforms, O95466-1: amino acid length is 1100, molecular weight is 121854 Da (predicted); O95466-2: amino acid length is 1104, molecular weight is 122409 Da (predicted); O95466-3: amino acid length is 1158, molecular weight is 128335 Da (predicted).Myristoylation mediates membrane localization and blebbing

  • Subunit

    Interacts with RAC1, PFN1 and PFN2 (By similarity).

  • SwissProt ID

    O95466

  • Gene ID
    752 [NCBI]
  • Synonyms

    C17orf1, C17orf1B, FMNL, FRL1, FMNL1, Formin-like protein 1, CLL-associated antigen KW-13, Leukocyte formin

[1]. Bai SW, et al. Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol. 2011 Aug 11;9:54. [Content Brief]

FMNL1 Antibody (YA8924) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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