FOLR2 Antibody (YA8190)

Cat. No.: HY-P88506: Fiche technique COA
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FOLR2 Antibody (YA8190) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FOLR2.

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Size	Stock	Quantité
20 μL	En stock	Estimated Time of Arrival: December 31
50 μL	En stock	Estimated Time of Arrival: December 31
100 μL	En stock	Estimated Time of Arrival: December 31
250 μL	Obtenir un devis

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description

Description

FOLR2 Antibody (YA8190) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FOLR2.

Host

Mouse

Clonality

Monoclonal

Masse moléculaire

Predicted band size: 29.1 kDa

Species Reactivity

Human

SwissProt ID

P14207

Immunogen

Human recombinant protein fragment corresponding to amino acids 20-221 of human FOLR2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Pureté	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release

Subcellular Localization：Cell membrane,Secreted

Expression：
Tissue_Specificity: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues
Induction: Up-regulated by retinoic acid

Isoforms & Post-Translational Modification：P14207: 255 amino acids, molecular weight 29280 Da.

Synonyms

BETA-HFR; FBP; FR-BETA; FR-P3; PL-1

Documentation

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Fiche technique (231 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)