FoxD3 Antibody (YA4864)
(Synonyms: FOXD3; HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis)FoxD3 Antibody (YA4864) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FoxD3.
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Host:
Mouse
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Application:
WB, IHC-P, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Monkey
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
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| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:10000 | 1:50-200 |
Product Details
FoxD3 Antibody (YA4864) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FoxD3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Monkey
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Calculated Molecular Weight Predicted band size: 48 kDa;
Purified recombinant fragment of human FoxD3 expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FoxD3 binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Negatively regulates transcription of transcriptional repressor RHIT/ZNF205. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis[1][2].
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:This gene is expressed in chronic myeloid leukemia, Jurkat T-cell leukemia, and teratoma cell lines, but not in other cell lines or normal tissues tested. -
Subunit
Interacts with POU5F1
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SwissProt ID
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Synonyms
FOXD3; HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis
Documentation
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