FoxD3 Antibody (YA4864)

Cat. No.: HY-P85172: Data Sheet User Guide for Antibodies
FAQs
Technical Support

FoxD3 Antibody (YA4864) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FoxD3.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

FoxD3 Antibody (YA4864) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FoxD3.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 48 kDa;

Species Reactivity

Human, Mouse, Monkey

SwissProt ID

Q9UJU5

Gene ID

27022 [NCBI]

Immunogen

Purified recombinant fragment of human FoxD3 expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor (PubMed:11891324). Also acts as a transcriptional activator (PubMed:11891324). Negatively regulates transcription of transcriptional repressor RHIT/ZNF205 (PubMed:22306510). Promotes development of neural crest cells from neural tube progenitors (PubMed:11891324). Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation (PubMed:11891324). Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis (PubMed:11891324)

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:This gene is expressed in chronic myeloid leukemia, Jurkat T-cell leukemia, and teratoma cell lines, but not in other cell lines or normal tissues tested.

Subunit：Interacts with POU5F1

Synonyms

FOXD3; HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis

Documentation

User Guide for Antibodies (1077 KB)