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Cat. No.: HY-P87484

FSTL3 Antibody (YA7171)

FSTL3 Antibody (YA7171) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FSTL3.

For research use only. We do not sell to patients.

Formulation:
Supplied in 0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:50-200	1:50-200	1:50-200

Description

FSTL3 Antibody (YA7171) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FSTL3.

Immunogen

KLH conjugated synthetic peptide derived from human FSTL3

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

FSTL3 is an Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such as activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10
Subcellular Localization

Secreted,Nucleus
Expression

Tissue_Specificity: Expressed in a wide range of tissues
Isoforms & Post-Translational Modification

O95633 has two isomers: O95633-1: 27663 Da (predicted); O95633-2: 24960 Da (predicted).
Subunit

Interacts with INHBA and INHBB
SwissProt ID

O95633