GLO1 Antibody (YA7718)

Cat. No.: HY-P88033: Fiche technique User Guide for Antibodies
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Technical Support

GLO1 Antibody (YA7718) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GLO1.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

GLO1 Antibody (YA7718) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GLO1.

Host

Rabbit

Clonality

Recombinant

Masse moléculaire

Predicted band size: 21 kDa;

Observed band size: 21 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human Predicted Reactivity: Mouse,Rat

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

Q04760

Immunogen

A synthesized peptide derived from human Lactoylglutathione lyase

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
FC FC: Flow Cytometry	1:50-100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200

Sensitivity	Endogenous	Pureté	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:20454679, PubMed:23122816, PubMed:9705294). Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (PubMed:19199007). Required for normal osteoclastogenesis (By similarity)

Isoforms & Post-Translational Modification：Q04760 has two isomers: Q04760-1: 20778 Da (predicted); Q04760-2: 19043 Da (predicted).
Glutathionylation at Cys-139 inhibits enzyme activity丨Phosphorylated at Thr-107 in the presence of CaMK2丨Exists in a nitric oxide (NO)-modified form

Subunit：Homodimer

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/baf3-cell.html [Content Brief]