Glucose 6 Phosphate Dehydrogenase Antibody (YA5705)
Glucose 6 Phosphate Dehydrogenase Antibody (YA5705) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-400 | 1:50-200 | 1:500-5000 |
Product Details
Glucose 6 Phosphate Dehydrogenase Antibody (YA5705) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Glucose 6 Phosphate Dehydrogenase.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 54 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 54 kDa
Synthesized peptide derived from human GLUT-1 AA range: 400-492
affinity chromatography.
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Glucose 6 Phosphate Dehydrogenase is a Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation[1][2][3][4][5][6][7].
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Subcellular Localization
Cell membrane; Multi-pass membrane protein; Melanosome; Photoreceptor inner segment
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Expression
Tissue_specificity:Protein levels were detected in red blood cells. Expression levels vary in various human tissues. -
Subunit
Interacts with GIPC (via PDZ domain) (By similarity). Found in a complex with ADD2, DMTN and SLC2A1. Interacts (via C-terminus cytoplasmic region) with DMTN isoform 2 (PubMed:18347014). Interacts with SNX27; the interaction is required when endocytosed to prevent degradation in lysosomes and promote recycling to the plasma membrane (PubMed:23563491). Interacts with STOM (PubMed:23219802). Interacts with SGTA (via Gln-rich region) (By similarity). Interacts with isoform 1 of BSG (PubMed:25957687)
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SwissProt ID
Documentation
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