GOT2 Antibody (YA3587)
(Synonyms: KAT4; KATIV; mitAAT)GOT2 Antibody (YA3587) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GOT2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Rat, Monkey
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Formulation:
Supplied in PBS with 0.05% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:10000 |
Product Details
GOT2 Antibody (YA3587) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GOT2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat, Monkey
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Observed Molecular WeightObserved band size: 43 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 48 kDa
Purified recombinant fragment of human GOT2 aa 30-430.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GOT2 catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids
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Subcellular Localization
Mitochondrion matrix; Cell membrane
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Expression
Induction:Up-regulated by long-time exposure to alcohol -
Isoforms & Post-Translational Modification
P00505 has 2 isomers: P00505-1: 47518 Da (predicted); P00505-2: 43030 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
KAT4; KATIV; mitAAT
Documentation
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