GPRC5B Antibody (YA2964)(PBS only)

Cat. No.: HY-P83219A: Data Sheet User Guide for Antibodies
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GPRC5B Antibody (YA2964) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GPRC5B.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

GPRC5B Antibody (YA2964) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GPRC5B.

Host

Rabbit

Molecular Weight

Predicted band size: 45 kDa;

Observed band size: 45 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9NZH0

Gene ID

51704 [NCBI]

Immunogen

A synthetic peptide of human GPRC5B aa363-376.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:8000
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：G-protein coupled receptor involved in the regulation of cell volume

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Cytoplasmic vesicle membrane; Multi-pass membrane protein

Expression：
Tissue_specificity:Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal cord as well as in dorsal root ganglia (DRG) . Expressed in glia limitans, ependymal cells, astrocyte cell bodies, the perivascular region in astrocyte endfeet, but not in neurons (PubMed:37143309) . In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach

Induction:By all-trans retinoic acid (ATRA)

Isoforms & Post-Translational Modification：Q9NZH0 has 2 isomers: Q9NZH0-1: 44795 Da (predicted); Q9NZH0-2: 44933 Da (predicted).

Research Field

Neuroscience

Synonyms

RAIG2; RAIG-2

Documentation

User Guide for Antibodies (1077 KB)