GST-Pi Antibody (YA976)
(Synonyms: GSTP1; FAEES3; GST3; Glutathione S-transferase P; GST class-pi; GSTP1-1)GST-Pi Antibody (YA976) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GST-Pi.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.70.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
GST-Pi Antibody (YA976) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GST-Pi.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 23 kDa
A synthesized peptide derived from human GST3
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.70.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GST-Pi is a Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration[1][2].
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Subcellular Localization
Cytoplasm; Mitochondrion; Nucleus
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Subunit
Homodimer. Interacts with CDK5
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SwissProt ID
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Synonyms
GSTP1; FAEES3; GST3; Glutathione S-transferase P; GST class-pi; GSTP1-1
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Research Field
Cardiovascular
Documentation
References
[1]. Bogaards JJ, et al. Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. Chem Res Toxicol. 1997 Mar;10(3):310-7. [Content Brief]
[2]. Brunnström A, et al. Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils. Lipids. 2011 Jan;46(1):69-79. [Content Brief]
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