GSTP1 - glutathione S-transferase pi 1 Gene

Also Known as PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 2950

About GSTP1

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:67,583,812-67,586,653 (from NCBI)

This gene has 8 transcripts (splice variants), 173 orthologues and 11 paralogues. Ubiquitous expression in esophagus (RPKM 400.7), thyroid (RPKM 188.1) and 24 other tissues.

Summary

Glutathione S-transferases (GSTs) are a family of Enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to Cancer, and Other Diseases. [provided by RefSeq, Jul 2008]

GSTP1 Products (1)

mRNA	Protein	Name
NM_000852.4	NP_000843.1	glutathione S-transferase P

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables S-nitrosoglutathione binding	IDA IDA: Inferred from direct assay	11533048	GOA
enables dinitrosyl-iron complex binding	IDA IDA: Inferred from direct assay	11533048	GOA
enables fatty acid binding	IPI IPI: Inferred from physical interaction	16624487	GOA
enables glutathione peroxidase activity	IDA IDA: Inferred from direct assay	16624487	GOA
enables glutathione transferase activity	IDA IDA: Inferred from direct assay	1540159	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16636664	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in glutathione derivative biosynthetic process	IDA IDA: Inferred from direct assay	9084911	GOA
involved in glutathione metabolic process	IDA IDA: Inferred from direct assay	1540159	GOA
involved in hepoxilin biosynthetic process	IDA IDA: Inferred from direct assay	21046276	GOA
involved in linoleic acid metabolic process	IDA IDA: Inferred from direct assay	16624487	GOA
involved in negative regulation of ERK1 and ERK2 cascade	IDA IDA: Inferred from direct assay	11408560	GOA
involved in negative regulation of JUN kinase activity	IDA IDA: Inferred from direct assay	16636664	GOA
involved in negative regulation of MAP kinase activity	IDA IDA: Inferred from direct assay	11408560	GOA
involved in negative regulation of biosynthetic process	IDA IDA: Inferred from direct assay	18962899	GOA
involved in negative regulation of extrinsic apoptotic signaling pathway	IDA IDA: Inferred from direct assay	16636664	GOA
involved in negative regulation of interleukin-1 beta production	IDA IDA: Inferred from direct assay	18962899	GOA
involved in negative regulation of monocyte chemotactic protein-1 production	IDA IDA: Inferred from direct assay	18962899	GOA
involved in negative regulation of nitric-oxide synthase biosynthetic process	IDA IDA: Inferred from direct assay	18962899	GOA
involved in negative regulation of protein kinase activity	IDA IDA: Inferred from direct assay	16636664	GOA
involved in negative regulation of tumor necrosis factor production	IDA IDA: Inferred from direct assay	18962899	GOA
involved in prostaglandin metabolic process	IDA IDA: Inferred from direct assay	9084911	GOA
involved in xenobiotic metabolic process	IDA IDA: Inferred from direct assay	1540159	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of TRAF2-GSTP1 complex	IDA IDA: Inferred from direct assay	16636664	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GSTP1 Protein Structure

GST_N

GST_C

0
100
200
210 a.a.

Protein Preferred Names	Protein Names
glutathione S-transferase P	GST class-pi

GSTP1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	GSTP1	P09211	KRTAP10-9	Homo sapiens	P60411	Validated Y2H	25416956
Intra	GSTP1	P09211	KRTAP10-9	Homo sapiens	P60411	Y2H Array	25416956
Intra	GSTP1	P09211	KRTAP10-9	Homo sapiens	P60411	Y2H Prey Pooling	25416956
Intra	GSTP1	P09211	KRTAP10-7	Homo sapiens	P60409	Y2H Prey Pooling	25416956
Intra	GSTP1	P09211	KRTAP10-7	Homo sapiens	P60409	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRTAP10-7	Homo sapiens	P60409	Validated Y2H	32296183
Intra	GSTP1	P09211	KRTAP10-7	Homo sapiens	P60409	Y2H Array	32296183
Intra	GSTP1	P09211	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Array	32296183
Intra	GSTP1	P09211	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	32296183
Intra	GSTP1	P09211	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRT83	Homo sapiens	P78385	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRT83	Homo sapiens	P78385	Validated Y2H	32296183
Intra	GSTP1	P09211	KRT83	Homo sapiens	P78385	Y2H Array	32296183
Intra	GSTP1	P09211	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	GSTP1	P09211	KRT33B	Homo sapiens	Q14525	Validated Y2H	32296183
Intra	GSTP1	P09211	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	GSTP1	P09211	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	MTUS2	Homo sapiens	Q5JR59-3	Validated Y2H	32296183
Intra	GSTP1	P09211	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	GSTP1	P09211	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Array	32296183
Intra	GSTP1	P09211	KRTAP1-1	Homo sapiens	Q07627	Validated Y2H	32296183
Intra	GSTP1	P09211	KRTAP1-1	Homo sapiens	Q07627	Y2H Array	32296183
Intra	GSTP1	P09211	KRTAP1-1	Homo sapiens	Q07627	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Array	32296183
Intra	GSTP1	P09211	KRTAP6-2	Homo sapiens	Q3LI66	Validated Y2H	32296183
Intra	GSTP1	P09211	LRP2BP	Homo sapiens	Q9P2M1	Y2H Array	32296183
Intra	GSTP1	P09211	LRP2BP	Homo sapiens	Q9P2M1	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	LRP2BP	Homo sapiens	Q9P2M1	Validated Y2H	32296183
Intra	GSTP1	P09211	NOTCH2NLC	Homo sapiens	P0DPK4	Validated Y2H	32296183
Intra	GSTP1	P09211	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Array	32296183
Intra	GSTP1	P09211	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	TGM1	Homo sapiens	P22735	Y2H Array	32296183
Intra	GSTP1	P09211	TGM1	Homo sapiens	P22735	Validated Y2H	32296183
Intra	GSTP1	P09211	TGM1	Homo sapiens	P22735	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	CARD10	Homo sapiens	Q9BWT7	Y2H Array	32296183
Intra	GSTP1	P09211	CARD10	Homo sapiens	Q9BWT7	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	GSTP1	P09211	KRTAP3-3	Homo sapiens	Q9BYR6	Y2H Array	32296183
Intra	GSTP1	P09211	KRTAP3-3	Homo sapiens	Q9BYR6	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRTAP3-3	Homo sapiens	Q9BYR6	Validated Y2H	32296183
Intra	GSTP1	P09211	ZNF655	Homo sapiens	Q8N720	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	ZNF655	Homo sapiens	Q8N720	Validated Y2H	32296183
Intra	GSTP1	P09211	ZNF655	Homo sapiens	Q8N720	Y2H Array	32296183
Intra	GSTP1	P09211	HOXA1	Homo sapiens	P49639	Validated Y2H	32296183
Intra	GSTP1	P09211	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	GSTP1	P09211	APPBP2	Homo sapiens	Q92624	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	APPBP2	Homo sapiens	Q92624	Validated Y2H	25416956
Intra	GSTP1	P09211	APPBP2	Homo sapiens	Q92624	Validated Y2H	32296183
Intra	GSTP1	P09211	APPBP2	Homo sapiens	Q92624	Y2H Array	32296183
Intra	GSTP1	P09211	FHL5	Homo sapiens	Q5TD97	Validated Y2H	32296183
Intra	GSTP1	P09211	FHL5	Homo sapiens	Q5TD97	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	FHL5	Homo sapiens	Q5TD97	Y2H Array	32296183
Intra	GSTP1	P09211	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Prey Pooling	25416956
Intra	GSTP1	P09211	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Array	25416956
Intra	GSTP1	P09211	NOTCH2NLA	Homo sapiens	Q7Z3S9	Validated Y2H	25416956
Intra	GSTP1	P09211	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	GSTP1	P09211	KRT31	Homo sapiens	Q15323	Validated Y2H	25416956
Intra	GSTP1	P09211	KRT31	Homo sapiens	Q15323	Validated Y2H	32296183
Intra	GSTP1	P09211	KRTAP3-1	Homo sapiens	Q9BYR8	Validated Y2H	32296183
Intra	GSTP1	P09211	KRTAP3-1	Homo sapiens	Q9BYR8	Y2H Prey Pooling	32296183
Intra	GSTP1	P09211	KRTAP3-1	Homo sapiens	Q9BYR8	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant GSTP1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70150	GSTP1 Protein, Human	AAH10915.1 (M1-Q210)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P71740	GSTP1 Protein, Human (P.pastoris, His)	P09211 (P2-Q210)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P72215	GSTP1 Protein, Human (His)	P09211 (P2-Q210)	≥ 90%, as determined by reducing SDS-PAGE.

GSTP1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81277	GST-Pi Antibody (YA975)	WB, IHC-F, IHC-P, ICC/IF, FC	Human
HY-P81277A	GST-Pi Antibody (YA976)	IHC-P	Human
HY-P81277AA	GST-Pi Antibody (YA976)(PBS only)	IHC-P	Human
HY-P84026	GST-Pi Antibody (YA3723)	WB, IHC-P, ICC/IF, FC, ELISA	Human
HY-P84026A	GST-Pi Antibody (YA3723)(PBS only)	WB, IHC-P, ICC/IF, FC, ELISA	Human
HY-P85935	GST-Pi Antibody (YA5627)	IHC-P, WB, ICC/IF, ELISA	Human, Mouse,

Related Diseases

Diseases	Alias
Kala-Azar 2	Kala-Azar, Susceptibility To, 2 KAZA2 Leishmaniasis, Visceral 2 Leishmaniasis, Visceral, Susceptibility To, 2
Papilloma	Papillomatosis
Squamous Cell Carcinoma	Epidermoid Carcinoma Squamous Cell Cancer Carcinoma, Squamous Cell Squamous Cell Skin Cancer Malignant Squamous Cell Tumor Squamous Carcinoma Squamous Cell Epithelioma Carcinoma Squamous Cell Neoplasms, Squamous Cell Squamous Cell Carcinoma - Category Malignant Squamous Cell Neoplasm Squamous Cell Carcinoma Of Skin
Hepatocellular Adenoma	Adenoma Hepatocellular
Deafness, X-Linked 7	X-Linked External Auditory Canal Atresia-Dilated Internal Auditory Canal-Facial Dysmorphism Syndrome DFNX7 X-Linked Deafness 7 Deafness, X-Linked, 7
Multiple Chemical Sensitivity	Environmental Illness 20th Century Disease Chemical Aids Idiopathic Environmental Illness Total Allergy Syndrome
Larynx Cancer	Laryngeal Carcinoma Laryngeal Cancer Laryngeal Neoplasm Carcinoma Of Larynx Malignant Neoplasm Of Larynx Cancer Of Larynx Laryngeal Neoplasms Cancer, Laryngeal
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Asbestosis	Idiopathic Interstitial Pneumonitis - From Asbestos Exposure Pulmonary Fibrosis - From Asbestos Exposure
Hellp Syndrome	Hemolysis, Elevated Liver Enzymes, Lowered Platelets Hemolysis, Elevated Liver Enzymes, Low Platelets In Pregnancy Hemolysis-Elevated Liver Enzymes-Low Platelets Syndrome Hellp - [Syndrome Of Haemolysis, Elevated Liver Enzymes And Low Platelet] Haemolysis-Elevated Liver Enzymes-Low Platelet Count Syndrome
Oral Mucosa Leukoplakia	Leukoplakia, Oral Leukoplakia Of Buccal Mucosa
Transitional Cell Carcinoma	Transitional Cell Neoplasm Carcinoma, Transitional Cell Transitional Carcinoma Transitional Cell Tumor Urothelial Cell Carcinoma Carcinoma Transitional Cell Transitional Cell Carcinoma Of Bladder
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Alcoholic Liver Cirrhosis	Alcoholic Cirrhosis Portal Cirrhosis Alcoholic Cirrhosis Of Liver Liver Cirrhosis, Alcoholic Laennec'S Cirrhosis Laennec'S Cirrhosis, Alcoholic Alcohol Cirrhosis Alcoholic Laennec Cirrhosis Alcoholic Cirrhosis Nos Etoh Cirrhosis Alcohol Hepatic Cirrhosis Alcohol Liver Cirrhosis Laennec Cirrhosis
Childhood-Onset Asthma	Childhood Asthma Asthma Childhood
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Exfoliation Syndrome	Pseudoexfoliation Glaucoma Pseudoexfoliation Syndrome Exfoliation Syndrome, Susceptibility To XFS Exfoliation Glaucoma Xfg Pseudoexfoliation Of The Lens Pexg Pexs Exfoliative Syndrome Glaucoma Capsulare Pex Pseudo-Exfoliation Syndrome
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Open-Angle Glaucoma	Glaucoma Simplex Pigmentary Glaucoma Wide-Angle Glaucoma Glaucoma, Open-Angle Open Angle Glaucoma Glaucoma Open-Angle Chronic Simple Glaucoma Coag - [Chronic Open-Angle Glaucoma] Csg - [Chronic Simple Glaucoma] Poag - [Primary Open-Angle Glaucoma] Oag - [Open-Angle Glaucoma] Chronic Glaucoma Chronic Open Angle Glaucoma Simple Glaucoma Chronic Noncongestive Glaucoma Ltg - [Low Tension Glaucoma] Noncongestive Glaucoma Nonobstructive Glaucoma Normal Pressure Glaucoma Primary Low Tension Glaucoma Low-Tension Glaucoma Residual Stage Low Tension Glaucoma Open Cleft Glaucoma
Oligospermia
Acetaminophen Metabolism
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Kidney Cancer	Renal Cancer Renal Carcinoma Kidney Neoplasm Malignant Neoplasm Of Kidney Except Pelvis Malignant Tumour Of Kidney Kidney Neoplasms Cancer, Kidney Cancer, Renal Malignant Neoplasm Of Kidney Renal Cell Carcinoma
Bronchitis	Chronic Bronchitis Acute Bronchitis Bronchitis, Chronic Acute Bronchitis And Bronchiolitis Chest Cold Chest Infection Ci - Chest Infection Recurrent Wheezy Bronchitis Bronchitis Chronic Lower Respiratory Tract Infection Acute Lower Respiratory Tract Infection Chronic Bronchitis Nos Senile Bronchitis Bronchitis Nos In Those Under L5 Years Of Age Bronchitis Nos
Childhood Acute Lymphocytic Leukemia	Childhood Acute Lymphoblastic Leukemia Childhood All Pediatric Acute Lymphoblastic Leukemia Lymphoblastic Leukemia Acute Childhood
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Bilateral Breast Cancer	Bilateral Breast Carcinoma
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Lung Benign Neoplasm	Lung Neoplasms Tumor Of The Lung Lung Tumor
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Aplastic Anemia	Aplastic Anemia, Susceptibility To Anemia Aplastic Idiopathic Aplastic Anemia Secondary Aplastic Anemia Idiopathic Bone Marrow Failure Aplastic Anemia Idiopathic AA Anemia, Aplastic Aplastic Anemia, Idiopathic Erythroid Aplasia Aa - [Aplastic Anaemia] Haematopoietic Aplasia Aleukia Haemorrhagica Anaemia Due To Decreased Red Cell Production Aplasia Bone Marrow Aplastic Bone Marrow Hypoplastic Anaemia Nos Myeloid Bone Marrow Aplasia Pancytopenia Panhaematopenia Hypoproliferative Anaemia Medullary Hypoplasia Red Blood Cells Hypoplastic Anaemia Panmyelophthisis Panhemocytopenia Refractive Hypoproliferative Anaemia Toxic Anaemia Toxic Aplastic Anaemia Aplastic Anaemia Due To Toxic Cause Idiopathic Aplastic Anaemia Nos
Xeroderma Pigmentosum, Complementation Group D	Xeroderma Pigmentosum, Group D Xpdc Xeroderma Pigmentosum Iv XPD Xeroderma Pigmentosum Group D Xeroderma Pigmentosum Viii Xp Group D Xp Group H Xp4 Xp8 Xph Xp, Group D Xp4 Xeroderma Pigmentosum Viii, Formerly Xp8, Formerly Xp, Group H, Formerly Xph, Formerly Xeroderma Pigmentosum Complementation Group D XP-D Xp-D/Cs
Liver Benign Neoplasm	Epithelial Hepatic And Intrahepatic Bile Duct Neoplasm
Lung Disease	Lung Diseases Disorder Of Lung Abnormality Of The Lung
Motor Neuron Disease	Anterior Horn Cell Disease Motor Neuron Diseases Mnd - [Motor Neurone Disease] Lou Gehrig Disease Creeping Palsy Creeping Paralysis Bulbar Motor Neuron Disease Bulbar Syndrome Anterior Horn Cell Disorder Hereditary Motor Neuron Disease
Pulmonary Disease, Chronic Obstructive	Chronic Obstructive Pulmonary Disease COPD Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Chronic Obstructive Lung Disease Chronic Obstructive Airway Disease Pulmonary Disease, Chronic Obstructive, Susceptibility To Cold Severe Early-Onset Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive Pulmonary Disease, Obstructive, Chronic, Susceptibility To Chronic Obstructive Pulmonary Disease Of Horses Common Cold Upper Respiratory Infections Copd - [Chronic Obstructive Pulmonary Disease] Coad - [Chronic Obstructive Airways Disease] Cold - [Chronic Obstructive Lung Disease] Chronic Airway Disease Nos Chronic Airways Limitation, Unspecified Chronic Obstructed Airway, Unspecified Chronic Obstructive Airway Disease, Unspecified Chronic Obstructive Airway, Unspecified Obstructive Lung Disease Nos Chronic Obstructive Lung Disease Nos Chronic Obstructive Lung Nos Obstructive Pulmonary Disease Nos Exacerbation Copd Nos Acute Exacerbation Copd
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Basal Cell Carcinoma	Basal Cell Cancer Basal Cell Neoplasm Basal Cell Carcinoma Of Skin Malignant Basal Cell Tumor Basal Cell Tumor Epithelioma Basal Cell Malignant Basal Cell Neoplasm Rodent Ulcer Carcinoma Basal Cell Neoplasms, Basal Cell Basal Cell Carcinomas Experimental Organism Basal Cell Carcinoma Nodulo-Ulcerative Basal Cell Carcinoma Basalioma Basal Cell Epithelioma Of Skin Bcc - [Basal Cell Carcinoma] Of Skin Rodent Ulcer Of Skin Rodent Ulcer Of Unspecified Site Basal Cell Epithelioma Of Unspecified Site
Occupational Asthma
Environmental Induced Asthma	Irritant Asthma
Esophageal Atresia	Tracheoesophageal Fistula Congenital Atresia Of Esophagus Congenital Imperforate Esophagus Imperforate Esophagus Oesophageal Atresia Te Fistula Tef Tracheoesophageal Fistula With Or Without Esophageal Atresia
Barrett Esophagus	Barrett'S Esophagus Barrett Esophagus/Esophageal Adenocarcinoma Barrett Metaplasia Barrett'S Ulcer Of Esophagus Ulcerative Esophagitis Barrett'S Esophagus With Esophagitis Barrett'S Oesophagus Barretts Syndrome Barrett Syndrome BE Peptic Ulcer Of Esophagus Adenocarcinoma Of Esophagus
Ehlers-Danlos Syndrome	Eds Cutis Hyperelastica Elastic Skin Ehlers-Danlos Syndromes Ed Syndrome Ehlers Danlos Syndrome Ehlers Danlos Disease Eds - [Ehlers-Danlos Syndrome]
Myelodysplastic Syndrome	Myelodysplastic Syndromes Myelodysplasia MDS Myelodysplastic Syndrome Included Myelodysplastic Syndrome, Susceptibility To, Included Myelodysplastic Syndrome, Somatic Myelodysplastic Syndrome, Susceptibility To
Tobacco Addiction	Nicotine Dependence Tobacco Addiction, Susceptibility To Nicotine Addiction Tobacco Use Disorder Smoking Habit Nicotine Dependence, Protection Against Nicotine Addiction, Protection From Cigarette Habituation Cigarette Habituation, Susceptibility To Smoking Habit, Susceptibility To Nicotine Dependence, Susceptibility To Nicotine Addiction, Susceptibility To Addiction, Tobacco, Susceptibility To Compulsive Tobacco User Syndrome Tobacco Dependence Tobacco Dependence Syndrome Cigarette Addiction Cigarette Dependence Smoking Addiction Smokers Syndrome
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Cataract	Cataracts Cat - [Cataract] Cataract Form Lens Opacity Lens Opacities
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Lethal Congenital Contracture Syndrome 4	LCCS4 Contracture Syndrome, Lethal, Congenital, Type 4
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Charcot-Marie-Tooth Disease	Cmt Hmsn Hereditary Motor And Sensory Neuropathy Pma Cmt - Charcot-Marie-Tooth Disease Charcot Marie Tooth Disease Charcot-Marie-Tooth Hereditary Neuropathy Charcot-Marie-Tooth Syndrome Peroneal Muscular Atrophy Hereditary Motor And Sensory Neuropathies
Diabetes Mellitus	Diabetes
Leukemia, Acute Lymphoblastic	Acute Lymphoblastic Leukemia ALL Acute Lymphocytic Leukemia Leukemia, Acute Lymphocytic, Susceptibility To, 1 Acute Lymphoblastic Leukaemia Precursor Lymphoblastic Lymphoma/Leukemia Precursor Lymphoid Neoplasm Leukemia, Acute Lymphoblastic, Susceptibility To B-Cell Acute Lymphoblastic Leukemia Leukemia, Acute Lymphocytic 1 Acute Lymphocytic Leukaemia Acute Lymphoblastic Leukemia/Lymphoma All1 Childhood Acute Lymphoblastic Leukemia Leukemia Acute Lymphoblastic 1 Leukemia Acute Lymphoblastic B-Hyperdiploid Leukemia Acute Lymphocytic Leukemia Acute Lymphocytic 1 Leukemia B-Cell Acute Lymphoblastic Leukemia T-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic, 3 ALL3 Lymphoblastic Leukemia Acute Leukemia, Acute, Lymphoblastic Precursor Cell Lymphoblastic Leukemia Lymphoma Leukemia, Lymphocytic, Acute, L1 Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Fanconi Anemia, Complementation Group A	Fanconi Anemia Fanconi Pancytopenia Fanconi Anemia Complementation Group A FANCA Fa Fanconi Panmyelopathy Fanconi'S Anemia Fanconi Anaemia Fanconi'S Anaemia Fanconi Hypoplastic Anemia Estren-Dameshek Variant Of Fanconi Anemia Estren-Dameshek Variant Of Fanconi Pancytopenia Fanconi Anemia Estren-Dameshek Variant Fanconis Anemia
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13634A	Ezatiostat		99.82%	Phase 2
HY-13634	Ezatiostat hydrochloride		/	Phase 2

Pre-clinical Phase

Bioactive Molecules (19)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-135318	NBDHEX		99.22%	Unkown
HY-115673	LAS17	Inhibitor	97.46%	Unkown
HY-13634B	TLK117	Inhibitor	99.86%	Unkown
HY-112534	GSTO-IN-2	Inhibitor	98.0%	Unkown
HY-P2961	Glutathione S-transferase		/	Unkown
HY-145413	BRD2889	Inhibitor	/	Unkown
HY-132913	Cyclopropenone probe 1		/	Unkown
HY-160455	GSTP1-1 inhibitor 1		/	Unkown
HY-169058	GSTP1-1 inhibitor 2	Inhibitor	/	Unkown
HY-178372	GSTO1-IN-4	Inhibitor	/	Unkown
HY-179217	GSTP1/M2-IN-1		/	Unkown
HY-182059	GSTP1-IN-1		/	Unkown
HY-RS05886	GSTP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W615446	GSTO1-IN-3	Inhibitor	/	Unkown
HY-16123	Canfosfamide hydrochloride	Chemical	/	Unkown
HY-167632	meso-Zeaxanthin		93.09%	Unkown
HY-N11778	Bequinostatin C		/	Unkown
HY-RS16643	Gstp1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23077	Gstp1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GSTP1	VGNC	VGNC:101091
Felis catus	GSTP1	VGNC	VGNC:103034
Rattus norvegicus	GSTP1	RGD	RGD:2758
Bos taurus	GSTP1	VGNC	VGNC:56267
Others	GSTP1	NCBI