HTR3B Antibody (YA3570)
(Synonyms: 5-HT3B)HTR3B Antibody (YA3570) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HTR3B.
-
Host:
Mouse
-
Isotype:
IgG2b
-
Application:
WB, ICC/IF, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:100-1:500 | 1:200-1:400 | 1:10000 |
Product Details
HTR3B Antibody (YA3570) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HTR3B.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 50 kDa
Purified recombinant fragment of human HTR3B (AA: extra 23-150) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2b
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS with 0.05% sodium azide
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
HTR3B forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
-
Subcellular Localization
Postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
-
Expression
Tissue_specificity:Expressed in the brain cortex, in the caudate nucleus, the hippocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta -
Isoforms & Post-Translational Modification
O95264 has 2 isomers: O95264-1: 50292 Da (predicted); O95264-2: 49285 Da (predicted).
N-glycosylation required for membrane localization -
Subunit
Forms homopentameric as well as heteropentameric serotonin-activated cation-selective channel complexes with HTR3A. The homomeric complex is not functional. Heteropentameric complexes display properties which resemble that of neuronal serotonin-activated channels in vivo
-
SwissProt ID
-
Synonyms
5-HT3B
Documentation
Powered by Bioz
