ID3 Antibody (YA7932)
(Synonyms: bHLHb25; HEIR-1)
Based on 1 Customer Validation
ID3 Antibody (YA7932) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ID3.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:50-250 | 1:100-250 | 1:100 |
Product Details
ID3 Antibody (YA7932) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ID3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 12.8 kDa
Full length human recombinant protein of human ID3 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ID3 transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain
Induction: By phorbol 12-myristate 13-acetate (PMA) -
Isoforms & Post-Translational Modification
Q02535: 119 amino acids, molecular weight 12999 Da.
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Subunit
Homodimer, and heterodimer with other HLH proteins
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SwissProt ID
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Synonyms
bHLHb25; HEIR-1
Documentation
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