ID3 Antibody (YA7932)

製品番号: HY-P88248: データシート User Guide for Antibodies
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ID3 Antibody (YA7932) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ID3.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

ID3 Antibody (YA7932) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ID3.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 12.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q02535

Immunogen

Full length human recombinant protein of human ID3 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-250
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain
Induction: By phorbol 12-myristate 13-acetate (PMA)

Isoforms & Post-Translational Modification：Q02535: 119 amino acids, molecular weight 12999 Da.

Subunit：Homodimer, and heterodimer with other HLH proteins

Synonyms

bHLHb25; HEIR-1

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/nih3t3-cell.html [Content Brief]