IKB beta Antibody (YA3088)

Cat. No.: HY-P83343: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

IKB beta Antibody (YA3088) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IKB beta.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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IKB beta Antibody (YA3088) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

IKB beta Antibody (YA3088) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IKB beta.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 38 kDa;

Observed band size: 48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q15653

Gene ID

4793 [NCBI]

Immunogen

A synthetic peptide of human IKB beta

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:20-1:50
FC FC: Flow Cytometry	1:20-1:50
IP IP: Immunoprecipitation	1:10-1:100

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation

Subcellular Localization：Cytoplasm; Nucleus

Expression：
Tissue_specificity:It was expressed in all the tissues tested.

Isoforms & Post-Translational Modification：Q15653 has 2 isomers: Q15653-1: 37771 Da (predicted); Q15653-2: 35530 Da (predicted).
Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation

Subunit：Interacts with THRB (via ligand-binding domain) (PubMed:7776974). Interacts with RELA and REL (By similarity). Interacts with COMMD1 (PubMed:16573520).

Database

Entrez Gene: 4793 Human ;

SwissProt: Q15653 Human ;

OMIM: 604495 Human

Research Field

Signal Transduction

Synonyms

NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

IKB beta Antibody (YA3088) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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IKB beta Antibody (YA3088)

IKB beta Antibody (YA3088) Featured Recommendations:

Product Detail

Background

Documentation

IKB beta Antibody (YA3088) Related Classifications

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