KDM4C Antibody (YA8589)
(Synonyms: GASC1; JHDM3C; JMJD2C; TDRD14C)KDM4C Antibody (YA8589) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KDM4C.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:50-250 | 1:100-250 |
Product Details
KDM4C Antibody (YA8589) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KDM4C.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Calculated Molecular Weight Predicted band size: 120.0 kDa
Full-length protein expressed in 293T cell transfected with human KDM4C expression vector
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KDM4C is a Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Overexpressed in several esophageal squamous cell carcinomas (ESCs) -
Isoforms & Post-Translational Modification
Q9H3R0 has four isomers: Q9H3R0-1: 119982 Da (predicted); Q9H3R0-2: 118416 Da (predicted); Q9H3R0-3: 91891 Da (predicted); Q9H3R0-4: 94376 Da (predicted).
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SwissProt ID
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Synonyms
GASC1; JHDM3C; JMJD2C; TDRD14C
Documentation
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