KIF22 Antibody (YA4273)
(Synonyms: KIF22; KID; OBP; KNSL4; OBP-1; OBP-2; A-328A3.2)KIF22 Antibody (YA4273) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KIF22.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in ascitic fluid containing 0.03% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
KIF22 Antibody (YA4273) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KIF22.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 73 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 73 kDa
Purified recombinant fragment of human KID aa 225-419.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in ascitic fluid containing 0.03% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KIF22 is a Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells[1].
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Subcellular Localization
Nucleus; Cytoplasm, cytoskeleton
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Expression
Tissue_specificity:It is expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes. -
Isoforms & Post-Translational Modification
Q14807 has 2 isomers: Q14807-1: 73262 Da (predicted); Q14807-2: 66307 Da (predicted).
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation -
Subunit
Interacts with FAM83D (PubMed:18485706). Interacts with SIAH1 (PubMed:11146551)
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SwissProt ID
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Synonyms
KIF22; KID; OBP; KNSL4; OBP-1; OBP-2; A-328A3.2
Documentation
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