KIF5A Antibody
(Synonyms: NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, Neuronal kinesin heavy chain, NKHC)KIF5A Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to KIF5A.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
KIF5A Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to KIF5A.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 129 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 117 kDa
Purified recombinant protein of human KIF5A
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KIF5A is a Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation
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Subcellular Localization
Cytoplasm, perinuclear region; Cytoplasm, cytoskeleton; Perikaryon
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Expression
Tissue_Specificity: Distributed throughout the CNS but is highly enriched in subsets of neurons. -
Isoforms & Post-Translational Modification
KIF5A has an amino acid length of 1032, molecular weight is 117378 Da.
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Subunit
Oligomer composed of two heavy chains and two light chains.
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SwissProt ID
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Synonyms
NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, Neuronal kinesin heavy chain, NKHC
Documentation
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