Matrilin-1 Antibody (YA3882)
(Synonyms: MAT; SAMS; MATA1; SAMS1; MAT1A)Matrilin-1 Antibody (YA3882) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Matrilin-1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF, ELISA
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Reactivity :
Human
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Formulation:
Supplied in ascitic fluid containing 0.03% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
Matrilin-1 Antibody (YA3882) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Matrilin-1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 54 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 54 kDa
Purified recombinant fragment of human MATN1 aa 427-496.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in ascitic fluid containing 0.03% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Matrilin-1 is an A major component of the extracellular matrix of non-articular cartilage. Binds to type 2 collagens and forms long concatenated protein networks as part of the extracellular matrix. Required for the network-like organization and bundling of collagen fibrils surrounding chondrocytes in the zones of maturation and hypertrophy. Required for mechanotransduction and adaption to mechanical loading in cartilage chondrocytes, resulting in an increase in expression of the extracellular matrix components ACAN and COL2A1. Acts as a moderator of angiogenesis in response to injury
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Subcellular Localization
Secreted, extracellular space, extracellular matrix
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Subunit
Homotrimer (By similarity). Part of a complex composed of MATN1 (via VWFA1 domain), type 2 collagens and type 6 collagens (PubMed:20729554).
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SwissProt ID
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Synonyms
MAT; SAMS; MATA1; SAMS1; MAT1A
Documentation
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