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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. MKLP1 Antibody (YA3233)

MKLP1 Antibody (YA3233)

Cat. No.: HY-P83488
User Guide for Antibodies Technical Support

MKLP1 Antibody (YA3233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MKLP1.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

MKLP1 Antibody (YA3233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MKLP1.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 110 kDa;
Observed band size: 110 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human MKLP1 aa814-827.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:200-500
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Solution
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro
Subcellular Localization：Nucleus; Cytoplasm, cytoskeleton, spindle; Midbody, Midbody ring
Expression：
Tissue_specificity:Widely expressed
Isoforms & Post-Translational Modification：Q02241 has 3 isomers: Q02241-1: 110059 Da (predicted); Q02241-2: 98105 Da (predicted); Q02241-3: 77699 Da (predicted).
Ubiquitinated. Deubiquitinated by USP8/UBPY
Subunit：Heterotetramer of two molecules each of RACGAP1 and KIF23. Found in the centralspindlin complex. Interacts with RACGAP1; the interaction is direct. Interacts with ECT2 and PRC1.
Database

Entrez Gene: 9493 Human

SwissProt: Q02241 Human

OMIM: 105600 Human

Research Field

Cell Biology
Synonyms
CHO1; KNSL5; MKLP1; MKLP-1
Documentation
User Guide for Antibodies (1077 KB)

MKLP1 Antibody (YA3233) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MKLP1 Antibody (YA3233)
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