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MPP1 Antibody (YA3077)

(Synonyms: MRG1; PEMP; AAG12; EMP55; DXS552E)

MPP1 Antibody (YA3077) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MPP1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • MPP1 Antibody (YA3077) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

MPP1 Antibody (YA3077) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MPP1.

  • Host Rabbit
  • Clonality Recombinant, Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 55 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 52 kDa
Species Reactivity Database

Entrez Gene: 4354 Human

SwissProt: Q00013 Human

Immunogen

A synthetic peptide of human MPP1

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MPP1 is essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity

  • Subcellular Localization

    Cell membrane; Lipid-anchor; Cell projection, stereocilium

  • Expression


    Tissue_specificity:Ubiquitous

  • Isoforms & Post-Translational Modification

    Q00013 has 3 isomers: Q00013-1: 52296 Da (predicted); Q00013-2: 49075 Da (predicted); Q00013-3: 49854 Da (predicted).
    Palmitoylated

  • Subunit

    Heterodimer with PALS1. Interacts with DLG5 and NF2. Interacts (via guanylate kinase-like domain) with WHRN (via third PDZ domain)

  • SwissProt ID

    Q00013

  • Gene ID
    4354 [NCBI]
  • Synonyms

    MRG1; PEMP; AAG12; EMP55; DXS552E

  • Research Field

    -

MPP1 Antibody (YA3077) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • MPP1 Antibody (YA3077) Product Image