MPP3 Antibody (YA8491)

Cat. No.: HY-P88807: Ficha de datos User Guide for Antibodies
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MPP3 Antibody (YA8491) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MPP3.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

MPP3 Antibody (YA8491) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MPP3.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 66.0 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q13368

Immunogen

Full length human recombinant protein of human MPP3 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (PubMed:24503895). Stabilizes HTR2C at the plasma membrane and prevents its desensitization. May participates in the maintenance of adherens junctions (By similarity)

Subcellular Localization：Cell membrane,Apical cell membrane,Cell junction, adherens junction

Expression：
Tissue_Specificity: Expressed in retina (at protein level) at the subapical region (SAR) adjacent to adherens junctions at the OLM, and at the OPL

Isoforms & Post-Translational Modification：Q13368 has two isomers: Q13368-1: 66152 Da (predicted); Q13368-2: 35559 Da (predicted).

Subunit：Interacts with HTR2C; this interaction stabilizes the receptor at the plasma membrane and prevents the desensitization of the HTR2C receptor-mediated calcium response (By similarity)

Synonyms

DLG3

Documentación

User Guide for Antibodies (1077 KB)