MPP3 Antibody (YA8491)
(Synonyms: DLG3)MPP3 Antibody (YA8491) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MPP3.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
MPP3 Antibody (YA8491) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MPP3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 66.0 kDa
Full length human recombinant protein of human MPP3 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MPP3 participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K). Stabilizes HTR2C at the plasma membrane and prevents its desensitization. May participates in the maintenance of adherens junctions[1].
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Subcellular Localization
Cell membrane,Apical cell membrane,Cell junction, adherens junction
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Expression
Tissue_Specificity: Expressed in retina (at protein level) at the subapical region (SAR) adjacent to adherens junctions at the OLM, and at the OPL -
Isoforms & Post-Translational Modification
Q13368 has two isomers: Q13368-1: 66152 Da (predicted); Q13368-2: 35559 Da (predicted).
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Subunit
Interacts with HTR2C; this interaction stabilizes the receptor at the plasma membrane and prevents the desensitization of the HTR2C receptor-mediated calcium response (By similarity)
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SwissProt ID
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Synonyms
DLG3
Documentation
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