Nanos3 Antibody (YA6883)
(Synonyms: NANO3_HUMAN antibody)Nanos3 Antibody (YA6883) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nanos3.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, ICC/IF, IHC-P
-
Reactivity :
Human
-
Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|---|
| Dilution Ratio | 1:2000 | 1:500 | 1:2000 |
Product Details
Nanos3 Antibody (YA6883) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nanos3.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 21 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size：21 kDa
Recombinant protein within human Nanos3 aa 1-192 (P60323-2).
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Nanos3 plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis
-
Subcellular Localization
Nucleus,Cytoplasm,Cytoplasm, Stress granule,Cytoplasm, P-body
-
Expression
Tissue_Specificity: Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, type A spermatogonia (SA), primary spermatocytes (S1), round spermatids (S3) and elongated spermatids -
Isoforms & Post-Translational Modification
P60323 has two isomers: P60323-1: 18844 Da (predicted); P60323-2: 20728 Da (predicted).
-
Subunit
Binds mRNA from germ cells
-
SwissProt ID
-
Synonyms
NANO3_HUMAN antibody
Documentation
Powered by Bioz
