Nanos3 Antibody (YA6883)

Cat. No.: HY-P87195: Data Sheet User Guide for Antibodies
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Nanos3 Antibody (YA6883) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nanos3.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Nanos3 Antibody (YA6883) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Nanos3.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size：21 kDa;

Observed band size: 21 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P60323

Immunogen

Recombinant protein within human Nanos3 aa 1-192 (P60323-2).

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:500
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:2000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis

Subcellular Localization：Nucleus,Cytoplasm,Cytoplasm, Stress granule,Cytoplasm, P-body

Expression：
Tissue_Specificity: Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, type A spermatogonia (SA), primary spermatocytes (S1), round spermatids (S3) and elongated spermatids

Isoforms & Post-Translational Modification：P60323 has two isomers: P60323-1: 18844 Da (predicted); P60323-2: 20728 Da (predicted).

Subunit：Binds mRNA from germ cells

Synonyms

NANO3_HUMAN antibody

Documentation

User Guide for Antibodies (1077 KB)