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  5. NSD3 Antibody (YA3074)

NSD3 Antibody (YA3074) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NSD3.

For research use only. We do not sell to patients.

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20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

NSD3 Antibody (YA3074) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NSD3.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 162 kDa;
Observed band size: 162 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human NSD3 aa1-59/1437.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
FC
FC: Flow Cytometry
1:50-1:100
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression
Subcellular Localization：Nucleus; Chromosome
Expression：
Tissue_specificity:Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung
Isoforms & Post-Translational Modification：Q9BZ95 has 5 isomers: Q9BZ95-1: 161613 Da (predicted); Q9BZ95-2: 156070 Da (predicted); Q9BZ95-3: 72621 Da (predicted); Q9BZ95-4: 154519 Da (predicted); Q9BZ95-5: 160314 Da (predicted).
Subunit：Interacts with BRD4 (PubMed:21555454, PubMed:29176719). Interacts (via KIKL motif) with BRD3 (via NET domain) (PubMed:29567837, PubMed:33592170)
Database

Entrez Gene: 54904 Human ; 234135 Mouse ; 290831 Rat

SwissProt: Q9BZ95 Human ; Q6P2L6 Mouse ;

OMIM: 607083 Human

Research Field

Epigenetics and Nuclear Signaling
Synonyms
Wolf Hirschhorn syndrome candidate 1 like 1; WHSC1L1; NSD3; pp14328; Histone-lysine N-methyltransferase NSD3; Protein whistle
Documentation
User Guide for Antibodies (1077 KB)

NSD3 Antibody (YA3074) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NSD3 Antibody (YA3074)
Cat. No.:
HY-P83329
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