NSD3 Antibody (YA3074)
(Synonyms: Wolf Hirschhorn syndrome candidate 1 like 1; WHSC1L1; NSD3; pp14328; Histone-lysine N-methyltransferase NSD3; Protein whistle)NSD3 Antibody (YA3074) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NSD3.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, FC
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
FC
FC: Flow Cytometry
|
|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:100 |
Product Details
NSD3 Antibody (YA3074) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NSD3.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 162 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 162 kDa
Entrez Gene: 54904 Human ; 234135 Mouse ; 290831 Rat
SwissProt: Q9BZ95 Human ; Q6P2L6 Mouse ;
OMIM: 607083 Human
A synthesized peptide derived from human NSD3 aa1-59/1437.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
NSD3 is a Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression
-
Subcellular Localization
Nucleus; Chromosome
-
Expression
Tissue_specificity:Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung -
Isoforms & Post-Translational Modification
Q9BZ95 has 5 isomers: Q9BZ95-1: 161613 Da (predicted); Q9BZ95-2: 156070 Da (predicted); Q9BZ95-3: 72621 Da (predicted); Q9BZ95-4: 154519 Da (predicted); Q9BZ95-5: 160314 Da (predicted).
-
Subunit
Interacts with BRD4 (PubMed:21555454, PubMed:29176719). Interacts (via KIKL motif) with BRD3 (via NET domain) (PubMed:29567837, PubMed:33592170)
-
SwissProt ID
-
Synonyms
Wolf Hirschhorn syndrome candidate 1 like 1; WHSC1L1; NSD3; pp14328; Histone-lysine N-methyltransferase NSD3; Protein whistle
-
Research Field
Epigenetics and Nuclear Signaling
Documentation
Powered by Bioz
