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PAX3 Antibody (YA3896)

(Synonyms: WS1; WS3; CDHS; HUP2)
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PAX3 Antibody (YA3896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAX3.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, ELISA

  • Reactivity :

    Human, Mouse

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • PAX3 Antibody (YA3896) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:10000

Product Details

Description

PAX3 Antibody (YA3896) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PAX3.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse
  • Observed Molecular Weight
    Observed band size: 56-60 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 53 kDa
Immunogen

Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PAX3 transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10[1].

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    P23760 has 8 isomers: P23760-1: 52968 Da (predicted); P23760-2: 24136 Da (predicted); P23760-3: 22743 Da (predicted); P23760-4: 44822 Da (predicted); P23760-5: 45217 Da (predicted); P23760-6: 53336 Da (predicted); P23760-7: 53464 Da (predicted); P23760-8: 55975 Da (predicted).

  • Subunit

    Can bind to DNA as a homodimer or a heterodimer with PAX7. Interacts with PAXBP1; the interaction links PAX3 to a WDR5-containing histone methyltransferase complex. Interacts with DAXX. Interacts with TBX18. Interacts with SOX10 (PubMed:21965087)

  • SwissProt ID

    P23760

  • Gene ID
    5077 [NCBI]
  • Synonyms

    WS1; WS3; CDHS; HUP2

PAX3 Antibody (YA3896) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • PAX3 Antibody (YA3896) Product Image