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  4. Monoclonal Antibodies Recombinant Antibodies
  5. PDLIM7 Antibody (YA1566)

PDLIM7 Antibody (YA1566)

Cat. No.: HY-P81821
User Guide for Antibodies Technical Support

PDLIM7 Antibody (YA1566) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDLIM7.

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사이즈 가격 재고 수량
20 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   견적 받기  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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  • 제품 설명

제품 설명

PDLIM7 Antibody (YA1566) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDLIM7.
Host

Rabbit
Clonality

Recombinant, Monoclonal
분자량
Predicted band size: 50 kDa;
Observed band size: 50 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant protein of human PDLIM7 aa122-223.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity)
Subcellular Localization：Cytoplasm; Cytoplasm, cytoskeleton
Expression：
Tissue_specificity:Isomer 1 and isomer 2 are widely expressed, but isomer 2 is predominant in skeletal muscle, while isomer 1 is more abundant in the lungs, spleen, leukocytes, and fetal liver.
Isoforms & Post-Translational Modification：Q9NR12 has 6 isomers: Q9NR12-1: 49845 Da (predicted); Q9NR12-2: 46510 Da (predicted); Q9NR12-3: 16034 Da (predicted); Q9NR12-4: 30411 Da (predicted); Q9NR12-5: 20514 Da (predicted); Q9NR12-6: 24413 Da (predicted).
Subunit：Binds via its LIM zinc-binding 3 domain (LIM 3) to endocytic codes of INSR, but not with those of IGF1R, LDLR, TFRC, or EGFR. Interacts with various PKC isoforms through the LIM zinc-binding domains. Binds to RET in a phosphorylation-independent manner via its LIM zinc-binding domain 2 (LIM 2). Probably part of a complex with SHC and the RET dimer. Interacts with TPM2. Interacts with TBX4 and TBX5 (By similarity)
Database

Entrez Gene: 9260 Human

SwissProt: Q9NR12 Human

OMIM: 605903 Human

Research Field

Signal Transduction
Synonyms
LIM mineralization protein; LMP; Protein enigma
각종 서류
User Guide for Antibodies (1077 KB)

PDLIM7 Antibody (YA1566) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
PDLIM7 Antibody (YA1566)
Cat. No.:
HY-P81821
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