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  4. Monoclonal Antibodies Recombinant Antibodies Modification Specific Antibodies
  5. Phospho-Bad (Ser112) Antibody (YA3099)

Phospho-Bad (Ser112) Antibody (YA3099)

Cat. No.: HY-P83354
COA
SDS
User Guide for Antibodies Technical Support

Phospho-Bad (Ser112) Antibody (YA3099) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Bad (Ser112).

For research use only. We do not sell to patients.

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50 μL In-stock
100 μL In-stock
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Phospho-Bad (Ser112) Antibody (YA3099) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Bad (Ser112).
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 18 kDa;
Observed band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human Bad RHS-pS-YPA.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Phosphorylated
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways
Subcellular Localization：Mitochondrion outer membrane; Cytoplasm
Expression：
Tissue_specificity:Expression in multiple organizations
Subunit：Forms heterodimers with the anti-apoptotic proteins, Bcl-X(L), Bcl-2 and Bcl-W.
Database

Entrez Gene: 572 Human ; 12015 Mouse ; 64639 Rat

SwissProt: Q92934 Human ; Q61337 Mouse ; O35147 Rat

OMIM: 603167 Human

Research Field

Cell Biology
Synonyms
BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter
Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Phospho-Bad (Ser112) Antibody (YA3099) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-Bad (Ser112) Antibody (YA3099)
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