PRMT2 Antibody (YA7866)(PBS only)

Cat. No.: HY-P88182A: Data Sheet User Guide for Antibodies
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PRMT2 Antibody (YA7866) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRMT2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

PRMT2 Antibody (YA7866) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRMT2.

Host

Mouse

Molecular Weight

Predicted band size: 48.9 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P55345

Immunogen

Full length human recombinant protein of human PRMT2 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation

Subcellular Localization：Cytoplasm,Nucleus,Nucleus,Cytoplasm,Nucleus,Nucleus, nucleolus,Nucleus,Cytoplasm,Nucleus

Expression：
Tissue_Specificity: Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord

Isoforms & Post-Translational Modification：P55345 has 7 isomers: P55345-1: 49042 Da (predicted); P55345-2: 31162 Da (predicted); P55345-3: 37167 Da (predicted); P55345-4: 32424 Da (predicted); P55345-5: 33543 Da (predicted); P55345-6: 25494 Da (predicted); P55345-7: 31193 Da (predicted).

Subunit：Self-associates

Synonyms

HRMT1L1

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/vero-cell.html [Content Brief]