PSMA5 Antibody (YA7141)

製品番号: HY-P87454: データシート User Guide for Antibodies
FAQs
Technical Support

PSMA5 Antibody (YA7141) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PSMA5.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

PSMA5 Antibody (YA7141) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PSMA5.

Host

Mouse

Clonality

Monoclonal,Recombinant

分子量

Predicted band size: 26.5kDa;

Species Reactivity

Human

SwissProt ID

P28066

Immunogen

Recombinant human PSMA5 (Fragment) (His-tagged).

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:50-500

Sensitivity	Endogenous	純度	affinity purified by Protein G
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

Subcellular Localization：Cytoplasm,Nucleus

Expression：
Tissue_Specificity: Expressed in fetal brain (at protein level)
Induction: Up-regulated in colon cancer cell lines. Up-regulated in fetal Down syndrome (DS) brain (at protein level). May be the target of the transcriptional activator NFE2L2

Isoforms & Post-Translational Modification：P28066 has two isomers: P28066-1: 26411 Da (predicted); P28066-2: 20035 Da (predicted).

Subunit：The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits

ドキュメンテーション

User Guide for Antibodies (1077 KB)

PSMA5 Antibody (YA7141) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PSMA5 Antibody (YA7141)

Product Detail

Background

説明

PSMA5 Antibody (YA7141) 関連分類

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