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PSMG2 Antibody (YA8181)(PBS only)

(Synonyms: CLAST3; HCCA3; HsT1707; MDS003; PAC2; TNFSF5IP1)

PSMG2 Antibody (YA8181) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PSMG2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PSMG2 Antibody (YA8181)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:100-250

Product Details

Description

PSMG2 Antibody (YA8181) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PSMG2.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 29.2 kDa
Immunogen

Full length human recombinant protein of human PSMG2 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PSMG2 is a Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization

  • Subcellular Localization

    Nucleus

  • Expression


    Tissue_Specificity: Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue

  • Isoforms & Post-Translational Modification

    Q969U7 has two isomers: Q969U7-1: 29396 Da (predicted); Q969U7-2: 26321 Da (predicted).
    Degraded by the proteasome upon completion of 20S proteasome maturation

  • Subunit

    Forms a heterodimer with PSMG1

  • SwissProt ID

    Q969U7

  • Synonyms

    CLAST3; HCCA3; HsT1707; MDS003; PAC2; TNFSF5IP1

PSMG2 Antibody (YA8181)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PSMG2 Antibody (YA8181)(PBS only) Product Image
    1/16
  • PSMG2 Antibody (YA8181)(PBS only) Product Image