QSOX1 Antibody (YA1121)
(Synonyms: Q6; QSCN6)QSOX1 Antibody (YA1121) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to QSOX1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.10.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 100-1:200 |
Product Details
QSOX1 Antibody (YA1121) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to QSOX1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 83 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 83 kDa
A synthesized peptide derived from human QSOX1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.10.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
QSOX1 catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration[1][2][3][4][5][6].
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Subcellular Localization
Golgi apparatus membrane; Single-pass membrane protein; Secreted; Secreted
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Expression
Tissue_specificity:Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney
Induction:Induced in quiescent cells just as fibroblasts begin to leave the proliferative cycle and enter quiescence -
Isoforms & Post-Translational Modification
O00391 has 2 isomers: O00391-1: 82578 Da (predicted); O00391-2: 66861 Da (predicted).
N-glycosylated (PubMed:17331072, PubMed:29757379). O-glycosylated on Thr and Ser residues (PubMed:29757379) -
Subunit
Monomer
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SwissProt ID
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Synonyms
Q6; QSCN6
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Research Field
Cell Biology
Documentation
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