QSOX1 - quiescin sulfhydryl oxidase 1 Gene

Homo sapiens

Also known as Q6; QSCN6

Gene ID: 5768 | Gene type: protein coding

About QSOX1

Cytogenetic location: 1q25.2 Genomic coordinates (GRCh38): 1:180,154,869-180,204,030 (from NCBI)

This gene has 4 transcripts (splice variants), 208 orthologues and 1 paralogue. Broad expression in gall bladder (RPKM 86.5), stomach (RPKM 79.3) and 25 other tissues.

Summary

This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

QSOX1 Products(2)

mRNA	Protein	Name
NM_001004128.3	NP_001004128.1	sulfhydryl oxidase 1 isoform b precursor
NM_002826.5	NP_002817.2	sulfhydryl oxidase 1 isoform a precursor

QSOX1 Protein Structure

Thioredoxin

Evr1_Alr

0
200
400
600
747 a.a.

Protein Preferred Names

Protein Names

sulfhydryl oxidase 1

quiescin Q6 sulfhydryl oxidase 1

Recombinant QSOX1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79367	QSOX1/Quiescin Q6 Protein, Human (His)	O00391 (S33-A546)	≥95%

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13750	Ebselen	Inhibitor	99.58%	Yes

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11509	QSOX1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	QSOX1	VGNC	VGNC:33605
Rattus norvegicus	QSOX1	RGD	RGD:68957
Canis familiaris	QSOX1	VGNC	VGNC:45238
Felis catus	QSOX1	VGNC	VGNC:69200
Macaca mulatta	QSOX1	VGNC	VGNC:106478
Mus musculus	QSOX1	MGD	MGI:1330818

Name
Email *

	Sorry, but the email address you supplied was invalid.