QSOX1 Antibody (YA1121)(PBS only)

Cat. No.: HY-P81376A: Data Sheet User Guide for Antibodies
FAQs
Technical Support

QSOX1 Antibody (YA1121) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to QSOX1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

QSOX1 Antibody (YA1121) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to QSOX1.

Host

Rabbit

Molecular Weight

Predicted band size: 83 kDa;

Observed band size: 83 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O00391

Gene ID

5768 [NCBI]

Immunogen

A synthesized peptide derived from human QSOX1

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:23867277, PubMed:30367560). Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:17331072, PubMed:22801504, PubMed:23867277, PubMed:30367560). In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:23704371, PubMed:23867277, PubMed:30367560)

Subcellular Localization：Golgi apparatus membrane; Single-pass membrane protein; Secreted; Secreted

Expression：
Tissue_specificity:Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney

Induction:Induced in quiescent cells just as fibroblasts begin to leave the proliferative cycle and enter quiescence

Isoforms & Post-Translational Modification：O00391 has 2 isomers: O00391-1: 82578 Da (predicted); O00391-2: 66861 Da (predicted).
N-glycosylated (PubMed:17331072, PubMed:29757379). O-glycosylated on Thr and Ser residues (PubMed:29757379)

Subunit：Monomer

Research Field

Cell Biology

Synonyms

Q6; QSCN6

Documentation

User Guide for Antibodies (1077 KB)