RAB20 Antibody (YA7169)
RAB20 Antibody (YA7169) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB20.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, ELISA
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:5000-10000 |
Product Details
RAB20 Antibody (YA7169) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB20.
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Host Mouse
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Clonality Monoclonal,Recombinant
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Calculated Molecular Weight Predicted band size: 26kDa;
Recombinant protein from human RAB20.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RAB20 is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB20 plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes
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Subcellular Localization
Golgi apparatus,Cytoplasmic vesicle, phagosome,Cytoplasmic vesicle, phagosome membrane
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Expression
Tissue_Specificity: Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level) -
Isoforms & Post-Translational Modification
Q9NX57: 234 amino acids, molecular weight 26277 Da.
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SwissProt ID
Documentation
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