RAB20 Antibody (YA7169)

Cat. No.: HY-P87482: Ficha de datos User Guide for Antibodies
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RAB20 Antibody (YA7169) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB20.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

RAB20 Antibody (YA7169) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RAB20.

Host

Mouse

Clonality

Monoclonal,Recombinant

Peso molecular

Predicted band size: 26kDa;

Predicted Reactivity

Human

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

Q9NX57

Immunogen

Recombinant protein from human RAB20.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-10000

Sensitivity	Endogenous	Pureza	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB20 plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes

Subcellular Localization：Golgi apparatus,Cytoplasmic vesicle, phagosome,Cytoplasmic vesicle, phagosome membrane

Expression：
Tissue_Specificity: Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level)

Isoforms & Post-Translational Modification：Q9NX57: 234 amino acids, molecular weight 26277 Da.

Documentación

User Guide for Antibodies (1077 KB)