Rab22A Antibody (YA7676)
(Synonyms: RAB22, RAB22A, Ras-related protein Rab-22A, Rab-22)Rab22A Antibody (YA7676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab22A.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IP
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Reactivity :
Human
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-200 | 1:20-50 |
Product Details
Rab22A Antibody (YA7676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rab22A.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman Predicted Reactivity: Mouse,RatNote: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 22 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 22 kDa
A synthesized peptide derived from human Rab22A
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Rab22A plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form[1][2].
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Subcellular Localization
Endosome membrane,Cell membrane,Early endosome,Late endosome,Cell projection, ruffle,Cytoplasmic vesicle,Cytoplasmic vesicle, phagosome,Cytoplasmic vesicle, phagosome membrane
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Isoforms & Post-Translational Modification
Q9UL26: 194 amino acids, molecular weight 21855 Da.
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Subunit
Interacts directly with ZFYVE20 (By similarity)
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SwissProt ID
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Synonyms
RAB22, RAB22A, Ras-related protein Rab-22A, Rab-22
Documentation
References