RAB24 Antibody (YA8148)

Cat. No.: HY-P88464: Data Sheet User Guide for Antibodies
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RAB24 Antibody (YA8148) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB24.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

RAB24 Antibody (YA8148) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RAB24.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 22.9 kDa

Species Reactivity

Human, Dog, Mouse

SwissProt ID

Q969Q5

Immunogen

Full length human recombinant protein of human RAB24 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB24 is an atypical RAB protein that presents low GTPase activity and thereby exists predominantly in the GTP-bound active state. RAB24 is required for the clearance of late autophagic vacuoles under basal conditions. It is not needed for starvation-induced autophagy. Involved in the modulation of meiotic apparatus assembly and meiotic progression during oocyte maturation, possibly through regulation of kinetochore-microtubule interaction

Subcellular Localization：Cytoplasm, cytosol,Membrane,Cytoplasmic vesicle, autophagosome membrane,Cytoplasm, perinuclear region,Cytoplasm, cytoskeleton, spindle

Expression：Induction: By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into postmitotic neurons (NTN2) (at protein level)

Isoforms & Post-Translational Modification：Q969Q5: 203 amino acids, molecular weight 23124 Da.

Subunit：Interacts with ZFYVE20 (PubMed:16034420)

Synonyms

member RAS oncogene family; RAB24; RAB24 gene product

Documentation

User Guide for Antibodies (1077 KB)