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Cat. No.: HY-P87765

Raf-B Antibody (YA7450)

Raf-B Antibody (YA7450) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Raf-B.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay	IP IP: Immunoprecipitation
Dilution Ratio	1:100-1:500	1:2000-1:10000	1:200-1:1000	1:5000-1:20000	1:50-1:200

Description

Raf-B Antibody (YA7450) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Raf-B.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 84 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 84 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG,Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Raf-B is a Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. Phosphorylates PFKFB2. May play a role in the postsynaptic responses of hippocampal neurons^[1]^[2]^[3]^[4].
Subcellular Localization

Nucleus,Cytoplasm,Cell membrane
Expression

Tissue_Specificity: Brain and testis
Isoforms & Post-Translational Modification

P15056: 766 amino acids, molecular weight 84437 Da.
Subunit

Monomer (PubMed:19710016)
SwissProt ID

P15056