RAIDD Antibody (YA10088)
RAIDD Antibody (YA10088) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to RAIDD.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IP, FC
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Reactivity :
Human, Rat
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Formulation:
Supplied in PBS(pH 7.3), 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:200 | 1:10-50 | 1:10-50 |
Product Details
RAIDD Antibody (YA10088) is a Rabbit-derived and non-conjugated IgG recombinant monoclonal antibody, targeting to RAIDD.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 23 kD
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 23 kD
Synthetic peptied of human RAIDD.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH 7.3), 50% glycerol, 0.05% BSA, and 0.05% Proclin300.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RAIDD is an Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis. Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway[1][2][3][4][5][6].
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_Specificity: Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. -
Isoforms & Post-Translational Modification
RAIDD has 2 isoforms, P78560-1: amino acid length is 199, molecular weight is 22745 Da (predicted); P78560-2: amino acid length is 103, molecular weight is 11826 Da (predicted).RAIDD 存在 2 个异构体，P78560-1：氨基酸个数为 199 个，分子量为 22745 Da (预测)；P78560-2：氨基酸个数为 103 个，分子量为 11826 Da (预测)。
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Subunit
Forms a complex named the PIDDosome with PIDD1 and CASP2.
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SwissProt ID
Documentation
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