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RNF39 Antibody (YA8604)(PBS only)

(Synonyms: HZF; HZFW; LIRF)

RNF39 Antibody (YA8604) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RNF39.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, IHC-P, ICC/IF

  • Reactivity :

    Human, Dog, Rat, Monkey, Mouse

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • RNF39 Antibody (YA8604)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:200 1:150 1:100

Product Details

Description

RNF39 Antibody (YA8604) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RNF39.

  • Host Mouse
  • Species Reactivity
    Human, Dog, Rat, Monkey, Mouse
  • Calculated Molecular Weight Predicted band size: 45.3 kDa
Immunogen

Full length human recombinant protein of human RNF39 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RNF39 plays an inhibitory role in anti-RNA viral innate immunity by targeting the adapter DDX3X and promoting its 'Lys-48'-linked polyubiquitination. Alternatively, enhances the cGAS-STING pathway activation by promoting 'Lys-63'-linked ubiquitination of STING1, facilitating the STING1-TBK1 complex formation and STING1 activation |(Microbial infection) Plays a positive role in human immunodeficiency virus (HIV-1) replication[1][2].

  • Subcellular Localization

    Cytoplasm

  • Expression


    Tissue_Specificity: Expressed in testis

  • Isoforms & Post-Translational Modification

    Q9H2S5 has three isomers: Q9H2S5-1: 45525 Da (predicted); Q9H2S5-2: 38179 Da (predicted); Q9H2S5-3: 27081 Da (predicted).

  • SwissProt ID

    Q9H2S5

  • Synonyms

    HZF; HZFW; LIRF

RNF39 Antibody (YA8604)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • RNF39 Antibody (YA8604)(PBS only) Product Image