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RTKN Antibody (YA7948)(PBS only)

(Synonyms: B5)

RTKN Antibody (YA7948) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RTKN.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • RTKN Antibody (YA7948)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:150-500 1:100-250

Product Details

Description

RTKN Antibody (YA7948) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to RTKN.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 61 kDa
Immunogen

Full length human recombinant protein of human RTKN produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RTKN mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures

  • Expression


    Tissue_Specificity: Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines

  • Isoforms & Post-Translational Modification

    Q9BST9 has three isomers: Q9BST9-1: 62667 Da (predicted); Q9BST9-2: 61229 Da (predicted); Q9BST9-3: 56666 Da (predicted).

  • Subunit

    Interacts via its C-terminal region with the TAX1BP3 PDZ domain

  • SwissProt ID

    Q9BST9

  • Synonyms

    B5

RTKN Antibody (YA7948)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • RTKN Antibody (YA7948)(PBS only) Product Image