SAPAP1 Antibody (YA5055)(PBS only)

Cat. No.: HY-P85363A: Data Sheet User Guide for Antibodies
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SAPAP1 Antibody (YA5055) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SAPAP1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SAPAP1 Antibody (YA5055) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SAPAP1.

Host

Mouse

Molecular Weight

Predicted band size: 109kDa;

Species Reactivity

Human

SwissProt ID

O14490

Gene ID

9229 [NCBI]

Immunogen

Purified recombinant fragment of human GKAP expressed in E. Coli. The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Part of the postsynaptic scaffold in neuronal cells

Subcellular Localization：Cell membrane; Peripheral membrane protein; Postsynaptic density; Synapse

Expression：
Tissue_specificity:Expressed in brain

Isoforms & Post-Translational Modification：O14490 has 7 isomers: O14490-1: 108873 Da (predicted); O14490-2: 75261 Da (predicted); O14490-3: 69969 Da (predicted); O14490-4: 76159 Da (predicted); O14490-5: 74058 Da (predicted); O14490-6: 76245 Da (predicted); O14490-7: 103581 Da (predicted).
Ubiquitinated by TRIM3; leading to proteasomal degradation

Subunit：Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1 (By similarity). Interacts with MPP2 (via the SH3-Guanylate kinase-like sub-module) (By similarity)

Synonyms

DLGAP1; DAP1; GKAP; Disks large-associated protein 1; DAP-1; Guanylate kinase-associated protein; hGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1

Documentation

User Guide for Antibodies (1077 KB)