Semaphorin 7A Antibody (YA3232)

Cat. No.: HY-P83487: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

Semaphorin 7A Antibody (YA3232) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Semaphorin 7A.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Semaphorin 7A Antibody (YA3232) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Semaphorin 7A Antibody (YA3232) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Semaphorin 7A.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 75 kDa;

Observed band size: 75 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O75326

Gene ID

8482 [NCBI]

Immunogen

Recombinant protein of human Semaphorin 7a aa45-648.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
FC FC: Flow Cytometry	1:200-1:500
IP IP: Immunoprecipitation	1:20-1:50

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes

Subcellular Localization：Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side

Expression：
Tissue_specificity:Protein levels were detected in keratinocytes and vascular endothelial cells of the skin. It was also expressed in fibroblasts, keratinocytes, melanocytes, placenta, testes, ovaries, spleen, brain, spinal cord, lungs, heart, adrenal glands, lymph nodes, thymus, intestines, and kidneys.

Induction:Up-regulated in UV-irradiated fibroblasts, but not in UV-irradiated keratinocytes

Isoforms & Post-Translational Modification：O75326 has 2 isomers: O75326-1: 74824 Da (predicted); O75326-2: 73364 Da (predicted).

Subunit：Interacts with ITGA1 and ITGB1 (Probable). Interacts with PLXNC1

Database

Entrez Gene: 8482 Human

SwissProt: O75326 Human

OMIM: 619874 Human

Research Field

Synonyms

JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

Semaphorin 7A Antibody (YA3232) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Semaphorin 7A Antibody (YA3232)

Semaphorin 7A Antibody (YA3232) Featured Recommendations:

Product Detail

Background

Documentation

Semaphorin 7A Antibody (YA3232) Related Classifications

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