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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. Septin 8 Antibody (YA3234)

Septin 8 Antibody (YA3234)

Cat. No.: HY-P83489
User Guide for Antibodies Technical Support

Septin 8 Antibody (YA3234) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Septin 8.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Septin 8 Antibody (YA3234) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Septin 8.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 56 kDa;
Observed band size: 56 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Hamster, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human Septin 8 aa64-77.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion (PubMed:15116257). Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity); Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP
Subcellular Localization：Cytoplasm; Cytoplasm, cytoskeleton; Synapse; Cell projection, axon; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Presynapse
Expression：
Tissue_specificity:Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary
Isoforms & Post-Translational Modification：Q92599 has 4 isomers: Q92599-1: 55756 Da (predicted); Q92599-2: 49814 Da (predicted); Q92599-3: 43519 Da (predicted); Q92599-4: 51178 Da (predicted).
Subunit：Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules.
Database

Entrez Gene: 23176 Human ; 20362 Mouse ;

SwissProt: Q92599 Human ; Q8CHH9 Mouse ; B0BNF1 Rat

OMIM: 608418 Human

Research Field

-
Synonyms
SEP2; SEPT8
Documentation
User Guide for Antibodies (1077 KB)

Septin 8 Antibody (YA3234) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Septin 8 Antibody (YA3234)
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